Intern exam

Hi All Interns.
Here are a few calculations to assist you in the test.
Good Luck!!!!
Question:
Mr Jola comes into the pharmacy with a prescription for 750ml of morphine solution containing 25mg/5ml. Master formula:
Morphine powder: 100g
Brilliant blue dye: 40ml
Aqua chloroform conc: 625ml
Hydroxybenzoate pres. Sol.: 150ml
Water to: 25L
How much of each ingredient would you use to prepare 750ml of the solution?
Solution:
Divide 750ml by 25000ml to get a factor of 0.03.
Take all items and multiply be 0.03
Morphine powder: 3g
Brilliant blue dye: 1.2ml
Aqua chloroform conc: 18.75ml
Hydroxybenzoate pres. Sol.: 4.5ml
Water to: 750ml
Question:
The supplier of methyl salicylate ointment is out of stock of the ointment. You are asked to make 35g of the ointment for Mrs Xuba. Calculate the quantities of each ingredient required. Master formula:
Methyl salicylate 500g
White beeswax 250g
Hydrous wool fat 250g
Solution:
Add all quantities together, you get a total of 1000g. Divide 35g by 1000g to get a factor of 0.035. Multiply all quantities by 0.035
Question:
A salicylic acid ointment base contains 12% w/w of salicylic acid and a water emulsifying base. What mass of ointment base is needed to prepare 200g of ointment?
Solution:
12%w/w is 12g salicylic acid in 100g of ointment therefore the amount of ointment used is 100-12 = 88. Therefore in 200g it is 88 X 2 = 176
Question:
Calulate the dose of active ingredient a patient receives on each occasion and each day?
Sudafed Elixir 150ml
3ml TDS
Solution:
Use MIMs to get the dosage of 30mg/5ml
Xmg/3ml
Cross multiply and X = 18mg/3ml per dose
And per day multiply by 3 to get 54mg
Question:
You are asked to reconstitute a bottle of ampicillin to create a suspension that contains 100mg/5ml ampicillin. The bottle contains 2.5mg ampicillin to be made up to 100ml. to what volume should it be made to, to give 100mg per5ml dose
Solution:
Have Want
2.5g in 100ml 100mg / 5ml
2500mg in Xml
100mg in 5ml
X = 125ml
Question:
If 37.5g od Digoxin is used to manufacture 150 000 tablets, what is the dose in µg of each tablet?
Solution:
37.5g makes 150 000 tablets
37.5X10^6 make 150 000 tablets
X makes 1 tablet
X = 250µg
Question:
Express 0.05% w/v Fluoride as parts per million (ppm)
Solution:
Ppm is 1g in 1000 000mls
0.05g in 1000ml
X in 1000 000ml
X = 500 ppm
Question:
If 50ml of a 1: 20 (w/v) solution of Aluminium Acetate is diluted to 1000ml, what is the percentage strength?
Solution:
Have Want
1g in 20ml 2.5g in 100ml
X in 50ml X in 100ml
X = 2.5g X = 0.25%

Community Service Pharmacists

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Rxmolemo committee

ALL INTERNS!!!

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If you have any queries or questions about your intern exam in July, please comment and the Rxmolemo Committee members will do their best to assist you.

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Rxmolemo Committee

Pharmacy Council Nominations

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We at Rxmolemo were wondering how you feel about the Pharmacy council nominations.
Don't you feel that we need to get young Pharmacists on the committee?
Please share your thoughts.

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